产品货号：
Z21670
中文名称：
NALP7/NLRP7抗体
英文名称：
Anti-NALP7/NLRP7 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NALP7/NLRP7 Antibody |
| 指标别名 | NLRP7;NALP7;NOD12;PYPAF3;NACHT;LRR and PYD domains-containing protein 7;Nucleotide-binding oligomerization domain protein 12;PYRIN-containing APAF1-like protein 3 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | NLRP7 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NALP7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NALP7.The immunogen is located within amino acids 90 - 140 of NALP7. |
| 计算分子量 | 112kDa |
| 成分 | NALP7 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NALP7 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | NOD proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins.NALP7,also known as PYPAF3,a member of the related PYRIN-containing APAF1-like proteins (PYPAFs/NALPs) is thought to play a crucial role in cell proliferation.NALP7 has a C-terminal leucine-rich repeat (LRR) region,an N-terminal Pyrin domain (PYD) followed by a NACHT domain,and a NACHT-associated domain.It is expressed in numerous tissues including uterus and ovary,with low levels in heart and brain.NALP7 inhibits caspase-1-dependent interleukin-1汕secretion and is a feedback regulator of interleukin-1汕secretion.Defects in the NALP7 gene are known to cause the formation of a hydatidiform mole (HYDM) and reduce the growth of carcinoma cell lines. |
| Uniprot ID | Q8WX94 |
| 基因名全称 | NLR family,pyrin domain containing 7 |
| 蛋白名全称 | NLR family,pyrin domain containing 7 |
| 推荐稀释比 | NALP7 antibody can be used for detection of NALP7 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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